PSA

Understanding the PSA Test and Its Relationship to Prostate Cancer


What Is the PSA Test?

The Prostate-Specific Antigen (PSA) test measures the level of PSA, a protein produced by the prostate gland, in the blood. While some PSA is normal, elevated levels can indicate prostate cancer, an enlarged prostate, or infection.

Who Should Consider the PSA Test?

- Men Over 50: Recommended to discuss testing with a GP.
- Higher-Risk Groups: Men aged 45+ who are Black or have a family history of prostate cancer.
- Men with Symptoms: Urinary or related symptoms should prompt a consultation.

Online Risk Checker Tool

Prostate Cancer UK offers a quick and easy online tool to assess your risk of prostate cancer. It asks simple questions about your age, ethnicity, and family history to determine your level of risk.

Check your risk here: prostatecanceruk.org/risk-checker

Benefits of PSA Testing

- Early Detection: Can identify prostate cancer before symptoms develop.
- Monitoring: Useful for tracking prostate health over time.

Limitations and Risks

- False Positives/Negatives: High PSA doesn't always mean cancer; normal PSA can miss cancer.
- Overdiagnosis: May lead to unnecessary treatment of harmless cancers.
- Treatment Side Effects: Can include urinary, bowel, and sexual issues.

What to Avoid Before a PSA Test

To ensure accurate results, avoid the following  before your test:
- Ejaculation: Avoid for 48hours before the test, can  temporarily raise PSA levels.
- Vigorous Exercise: Avoid for 48hours before the test,  especially cycling or activities that put pressure on the prostate.
- Prostate Manipulation: Such as per rectal exams or catheterization—delay testing if recently performed.
- Urinary Tract Infections (UTIs): Wait until the infection is fully treated.

 Some medications like finasteride can affect PSA- Always inform your doctor about recent procedures, infections, or medications.

Current Guidelines

Prostate Cancer UK encourages informed decision-making. While there's no UK-wide screening program, men—especially in higher-risk groups—are urged to talk with their GP about the risks and benefits of PSA testing.

Conclusion

The PSA test is a helpful indicator of prostate health but not a definitive diagnostic tool. For more information, visit: https://prostatecanceruk.org/

Page last reviewed: 01 July 2025
Page created: 01 July 2025